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Sources: Pyruvate; (C00022)
Acetyl-CoA; (C00024)
Target:L-Leucine; (C00123)
Z: 0.5
Composite map: C00024->C00123:[49->1,49->3,50->2]
Showing 1 best reactions for each rpair.
| RPAIR | Reaction | Score | Seq1 | Seq2 | Evalue | ECs | Equation |
|---|---|---|---|---|---|---|---|
| RP06172 | R00472 | 966 | TRIRE0079271 | P28345|MASY_NEUCR | 0.0 | 2.3.3.9 | CoA; + S)-Malate; <=> Acetyl-CoA; + Glyoxylate; + H2O; |
| RP00424 | R01090 | 480 | TRIRE0045459 | P47176|BCA2_YEAST | e-135 | 2.6.1.42 | 2-Oxoglutarate; + L-Leucine; <=> L-Glutamate; + 4-Methyl-2-oxopentanoate; |
| RP03767 | R04138 | 554 | TRIRE0064345 | Q9LDD8|MCCB_ARATH | e-157 | 6.4.1.4 | HCO3-; + ATP; + 3-Methylcrotonyl-CoA; <=> 3-Methylglutaconyl-CoA; + Orthophosphate; + ADP; |
| RP11035 | R01702 | 414 | TRIRE0056726 | Q8HXY4|ODBA_MACFA | e-115 | 1.2.4.4 | 4-Methyl-2-oxopentanoate; + Enzyme N6-(lipoyl)lysine; <=> CO2; + Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] |
| RP01456 | R01360 | 275 | TRIRE0120786 | Q29448|HMGCL_BOVIN | 1e-73 | 4.1.3.4 | S)-3-Hydroxy-3-methylglutaryl-CoA; <=> Acetoacetate; + Acetyl-CoA; |
| RP01457 | R01360 | 275 | TRIRE0120786 | Q29448|HMGCL_BOVIN | 1e-73 | 4.1.3.4 | S)-3-Hydroxy-3-methylglutaryl-CoA; <=> Acetoacetate; + Acetyl-CoA; |
| RP00079 | R00342 | 427 | TRIRE0123729 | P17505|MDHM_YEAST | e-119 | 1.1.1.37 | S)-Malate; + NAD+; <=> Oxaloacetate; + NADH; + H |
| RP11034 | R07601 | 414 | TRIRE0056726 | Q8HXY4|ODBA_MACFA | e-115 | 1.2.4.4 | Thiamin diphosphate; + 4-Methyl-2-oxopentanoate; <=> CO2; + 3-Methyl-1-hydroxybutyl-ThPP; |
| RP00729 | R04096 | 450 | TRIRE0108732 | Q9FS87|IVD2_SOLTU | e-126 | 1.3.99.10 | 3-Methylbutanoyl-CoA; + Acceptor; <=> 3-Methylcrotonyl-CoA; + Reduced acceptor; |
| RP05859 | R01702 | 414 | TRIRE0056726 | Q8HXY4|ODBA_MACFA | e-115 | 1.2.4.4 | 4-Methyl-2-oxopentanoate; + Enzyme N6-(lipoyl)lysine; <=> CO2; + Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] |
| RP00026 | R00235 | 1128 | TRIRE0073774 | P16929|ACSA_NEUCR | 0.0 | 6.2.1.1 | CoA; + ATP; + Acetate; <=> Acetyl-CoA; + Diphosphate; + AMP; |
| RP01666 | R08566 | 41 | TRIRE0081576 | O58413|VORA_PYRHO | 0.011 | 1.2.7.7 | CoA; + 4-Methyl-2-oxopentanoate; + Oxidized ferredoxin <=> 3-Methylbutanoyl-CoA; + CO2; + H+ + Reduced ferredoxin |
| RP04318 | R00224 | 759 | TRIRE0121534 | Q4WXX9|PDC_ASPFU | 0.0 | 4.1.1.1 | Pyruvate; <=> CO2; + Acetaldehyde; |
| RP05729 | R00341 | 999 | TRIRE0124115 | Q7RVS9|PPCK_NEUCR | 0.0 | 4.1.1.49 | Oxaloacetate; + ATP; <=> CO2; + Phosphoenolpyruvate; + ADP; |
| RP01963 | R02085 | 128 | TRIRE0061442 | Q9JLZ3|AUHM_MOUSE | 1e-29 | 4.2.1.18 | S)-3-Hydroxy-3-methylglutaryl-CoA; <=> 3-Methylglutaconyl-CoA; + H2O; |
| RP00128 | R00710 | 753 | TRIRE0078683 | P40108|ALDH_CLAHE | 0.0 | 1.2.1.3 | Acetaldehyde; + NAD+; + H2O; <=> NADH; + Acetate; + H |
Pathway diagram (see pathway with molecule structures instead)
